Publications

Publications in peer reviewed journals

Mahmud T, Peakman M, Senaldi G, Black C, Vergani D. Antireticulin antibodies in systemic sclerosis. Ann Rheum Dis 1990; 49: 177-180.

Mahmud T, Comer M, Roberts K, Scott DL. Patients’ Knowledge of Drug Therapy: Implications for Care. Clinical Rheumatol 1995; 14: 627-30.

Mahmud T, Scott DL, Bjarnason I. A unifying hypothesis for the mechanism of NSAID related gastrointestinal toxicity. Ann Rheum Dis 1996; 55: 11-13.

Mahmud T, Wrigglesworth JM, Scott DL, Bjarnason I. Mitochondrial function and modification of NSAID carboxyl moiety. Inflammopharmacology 1996; 4: 189-194.

Mahmud T, Rafi SS, Scott DL, Wrigglesworth JM, Bjarnason I. NSAIDs and uncoupling of oxidative phosphorylation. Arthritis Rheum, 1996; 39: 1998-2003.

Somasundaram S, Rafi S, Jacob M, Sigthorsson G, Mahmud T, et al. Intestinal tolerability of nitrobutoxyl-flurbiprofen in rats. Gut 1997; 40: 608-613.

Somasundaram S, Rafi S, Hayller J, Sigthorsson G, Jacob M, Price AB, MacPherson A, Mahmud T, et al. Mitochondrial damage: a possible mechanism of the “topical” phase of NSAID induced injury to the rat intestine. Gut 1997; 41: 344-353.

Mahmud T, Somasundaram S, Sigthorsson G, et al. Enantiomers of flurbiprofen can distinguish key pathophysiological steps of NSAID entropathy in the rat. Gut 1998; 43: 775-782.

Sigthorsson G, Jacob M, Wrigglesworth J, Somasundaram S, Tavares I, Foster R, Roseth A, Rafi S, Mahmud T, et al. Comparison of indomethacin and nimusilide, a selective cyclooxygenase-2 inhibitor, on key pathophysiologic steps in the pathologenesis of nonsteroidal anti-inflammatory drug enteropathy in the rat. Scand J Gastroenterol 1998; 33: 728-735.

Sigthorsson G, Tibble J, Mahmud T, Bjarnason I. NSAID-induced gastrointestinal damage: the biochemical consequences of the ‘ion trapping’ hypothesis. Inflammopharmacology 2000; 8: 31-41.

Sigthorsson G, Thiodleifsson B, Mahmud T, Bjarnason I. Gastrointestinal tolerability of nimesulide, a selective cyclooxygenase-2 inhibitor, in experimental animals and man. Inflammopharmacology 2000; 8: 171-87.

Book article

Mahmud T, Wrigglesworth JM, Scott DL, Bjarnason I. Mitochondrial function and NSAID carboxyl moiety. Side effects of anti-inflammatory drugs IV, p243-248. Rainsford KD (Ed) 1997 Kluwer Academic Publishers, Great Britain.

Abstracts and minor peer review publications

Mahmud T, Senaldi G, Peakman M, McWhirter A, Black C, Vergani D. Characterisation of autoantibodies in progressive systemic sclerosis.  Br J Rheumatol 1987; 26(Suppl): 77.

Peakman M, Mahmud T, Vergani D, [letter] Ann Rheum Dis 1992; 51: 1104.

Mahmud T, Scott DL, Comer M, Roberts K, Hopkins A. Patients’ knowledge of drug therapy: implications for care. Br J Rheumatol 1994; 33(Suppl ): 151.

Mahmud T, Rafi S, Scott DL, Wrigglesworth JM, Bjarnason I. Uncoupling of oxidative phosphorylation by NSAIDs relates to their pKa. Br J Rheumatol 1995; 34(Suppl): S2.

Mahmud T, Wrigglesworth JM, Rafi S, Scott DL, Bjarnason I. Uncoupling of oxidative phosphorylation by non-steroidal anti-inflammatory drugs (NSAIDs) related to ionisable moiety and can be altered by modification of carboxylic group. Arthritis Rheum 1995; 38(Suppl): S207.

Rafi S, Somasundaram S, Mahmud T, et al.  The importance of uncoupling of mitochondrial oxidative phosphorylation in NSAID-induced gastrointestinal damage. Arthritis Rheum 1995; 38(Suppl): S207.

Mahmud T, at al. Non-acidic pro-NSAIDs and COX-2 inhibitors do not uncouple mitochondrial oxidative phosphorylation. Br J Rheumatol 1996; 35(Suppl): S222.

Mahmud T, Scott DL, Crane R, Bjarnason I. NSAID-induced permeability change in Whites and non-white ethnic subjects. Arthritis Rheum 1996; 35(Suppl): S439.

Mahmud T, Hughes GVR. Intravenous immunoglobulin in the treatment of refractory adult Still’s disease.  J Rheum 1999; 26: 2067-8.

Mahmud T, Allen M.  British Society for Rheumatology guide for junior doctors on becoming a rheumatologist. BSR 1997.

Mahmud T. Early Vs delayed treatment in patients with recent-onset RA. Global Healthcare: Advanced Medical Technologies 2004; 78-82.

Thomas LM, Hull RG et al, Mahmud T. How useful is Intramuscular DepoMedrone? EULAR 2005, Ann Rheum Dis 2005.

Khan A, Mahmud T, Leak AM. Rituximab is more effective in active sero-positive RA than sero-negative RA patients. Arth Rheum 2010.

Manuscript in preparation

Mahmud T, Crump B. Systematic and real-time patient feedback in improving clinical service.